解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:Iron deficiency is the most widespread nutrient deficiency and an important cause of developmental impairment in children. However, some studies have indicated that iron deficiency can also protect against malaria, which is a leading cause of childhood morbidity and mortality in large parts of the world. Thi...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-018-2186-8
更新日期:2018-01-16 00:00:00
abstract:BACKGROUND:New World vultures (Cathartiformes: Cathartidae) are obligate scavengers comprised of seven species in five genera throughout the Americas. Of these, turkey vultures (Cathartes aura) and black vultures (Coragyps atratus) are the most widespread and, although ecologically similar, have evolved differences in ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-2165-5
更新日期:2018-01-08 00:00:00
abstract:BACKGROUND:The number of Plasmodium falciparum malaria cases around the world has decreased substantially over the last 15 years, but with the spread of resistance against anti-malarial drugs and insecticides, this decline may not continue. There is an urgent need to consider alternative, accelerated strategies to elim...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-2130-3
更新日期:2017-11-28 00:00:00
abstract:BACKGROUND:Since Plasmodium falciparum transmission relies exclusively on sexual-stage parasites, several malaria control strategies aim to disrupt this step of the life cycle. Thus, a better understanding of which individuals constitute the primary gametocyte reservoir within an endemic population, and the temporal dy...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-2123-2
更新日期:2017-11-21 00:00:00
abstract:BACKGROUND:There is growing concern that malaria vector resistance to pyrethroid insecticides may reduce the effectiveness of long-lasting insecticidal nets (LLINs). Combination LLINs are designed to control susceptible and pyrethroid-resistant mosquito populations through a mixture of pyrethroid with piperonyl butoxid...
journal_title:Malaria journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12936-017-2124-1
更新日期:2017-11-21 00:00:00
abstract:BACKGROUND:As in other countries of the Greater Mekong Sub-region (GMS), the private health sector constitutes a significant avenue where malaria services are provided and presents a unique opportunity for public-private collaboration. In September 2008, a public-private mix (PPM) strategy was launched initially in fou...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-2104-5
更新日期:2017-11-13 00:00:00
abstract:BACKGROUND:The widespread use of indoor-based malaria vector control interventions has been shown to alter the behaviour of vectors in Africa. There is an increasing concern that such changes could sustain residual transmission. This study was conducted to assess vector species composition, feeding behaviour and their ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-2098-z
更新日期:2017-11-06 00:00:00
abstract:BACKGROUND:A recent randomized trial showed that artemisinin-naphthoquine (AN) was non-inferior to artemether-lumefantrine (AL) for falciparum malaria and superior for vivax malaria in young Papua New Guinean children. The aim of this study was to compare the cost-effectiveness of these two regimens. METHODS:An increm...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-2081-8
更新日期:2017-10-30 00:00:00
abstract:BACKGROUND:Malaria vector control in Tanzania is based on use of long-lasting insecticide treated nets (LLINs) and indoor residual spraying (IRS), which both rely on the use of chemical insecticides. The effectiveness of these control tools is endangered by the development of insecticide resistance in the major malaria...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-2087-2
更新日期:2017-10-30 00:00:00
abstract:BACKGROUND:Malaria remains a worldwide public health concern and, in Colombia, despite the efforts to stop malaria transmission, the incidence of cases has increased over the last few years. In this context, it is necessary to evaluate vector diversity, infection rates, and spatial distribution, to better understand di...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-2076-5
更新日期:2017-10-27 00:00:00
abstract:BACKGROUND:The effectiveness of malaria prevention with long-lasting insecticidal nets and indoor residual spraying is limited by emerging insecticide resistance, evasive mosquito behaviours that include outdoor biting, sub-optimal implementation and inappropriate use. New vector control interventions are required and ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-2056-9
更新日期:2017-10-11 00:00:00
abstract:BACKGROUND:Insect vectors, namely mosquitoes (Diptera: Culicidae), are compulsory for malaria parasites (Plasmodium spp.) to complete their life cycle. Despite this, little is known about vector competence of different mosquito species for the transmission of avian malaria parasites. METHODS:In this study, nested PCR ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-2035-1
更新日期:2017-09-29 00:00:00
abstract::After publication of the article [1], it has been brought to our attention that a funding acknowledgement has been omitted from the original article. The authors would like to include the following, "The study was undertaken as part of the Target Malaria consortium, which receives core funding from the Bill & Melinda ...
journal_title:Malaria journal
pub_type: 已发布勘误
doi:10.1186/s12936-017-2030-6
更新日期:2017-09-19 00:00:00
abstract:BACKGROUND:Insecticide resistance is the major emerging challenge facing the malaria vector control programmes in Tanzania. Proper monitoring and detection is of paramount importance guiding the vector control programmes. This paper presents the effect of mosquito aging on insecticide resistance status in Anopheles ara...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-2022-6
更新日期:2017-09-11 00:00:00
abstract:BACKGROUND:As Swaziland progresses towards national malaria elimination, the importation of parasites into receptive areas becomes increasingly important. Imported infections have the potential to instigate local transmission and sustain local parasite reservoirs. METHODS:Travel histories from Swaziland's routine surv...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-2004-8
更新日期:2017-09-08 00:00:00
abstract:BACKGROUND:Anti-malarial drugs are an important tool for malaria control and elimination. Alongside their direct benefit in the treatment of disease, drug use has a community-level effect, clearing the reservoir of infection and reducing onward transmission of the parasite. Different compounds potentially have differen...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1988-4
更新日期:2017-08-16 00:00:00
abstract:BACKGROUND:Mosquito-feeding assays are important tools to guide the development and support the evaluation of transmission-blocking interventions. These functional bioassays measure the sporogonic development of gametocytes in blood-fed mosquitoes. Measuring the infectivity of low gametocyte densities has become increa...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1959-9
更新日期:2017-08-05 00:00:00
abstract:BACKGROUND:Understanding the dynamics of malaria transmission in diverse endemic settings is key for designing and implementing locally adapted and sustainable control and elimination strategies. A parasitological and epidemiological survey was conducted in September-October 2012, as a baseline underlying a 3-year popu...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1957-y
更新日期:2017-08-04 00:00:00
abstract:BACKGROUND:Indonesia is home to a variety of malaria vectors whose specific bionomic traits remain largely uncharacterized. Species-specific behaviours, such as host feeding preferences, impact the dynamics of malaria transmission and the effectiveness of vector control interventions. METHODS:To examine species-specif...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1950-5
更新日期:2017-08-02 00:00:00
abstract:BACKGROUND:An intensive effort to control malaria in Zimbabwe has produced dramatic reductions in the burden of the disease over the past 13 years. The successes have prompted the Zimbabwe's National Malaria Control Programme to commit to elimination of malaria. It is critical to analyse the changes in the morbidity tr...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1939-0
更新日期:2017-07-24 00:00:00
abstract:BACKGROUND:Seasonal malaria chemoprevention (SMC) is a new strategy to reduce malaria burden in young children in Sahelian countries. It consists of the administration of full treatment courses of sulfadoxine-pyrimethamine plus amodiaquine to children at monthly intervals during the malaria season. However, it is not c...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1935-4
更新日期:2017-07-18 00:00:00
abstract:BACKGROUND:Donor financing for malaria has declined since 2010 and this trend is projected to continue for the foreseeable future. These reductions have a significant impact on lower burden countries actively pursuing elimination, which are usually a lesser priority for donors. While domestic spending on malaria has be...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1890-0
更新日期:2017-07-14 00:00:00
abstract:BACKGROUND:Malaria is seasonal and this may influence the number of children being treated as outpatients in hospitals. The objective of this study was to investigate the degree of seasonality in malaria in lakeshore and highland areas of Zomba district Malawi, and influence of climatic factors on incidence of malaria....
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1913-x
更新日期:2017-07-03 00:00:00
abstract::Spain declared the elimination of malaria in 1964. In non-endemic areas, the overwhelming majority of malaria cases are acquired abroad, and locally acquired infections are rare events. In Spain, malaria is a statutorily notifiable disease. During these fifty years more than ten thousand malaria cases have been report...
journal_title:Malaria journal
pub_type: 杂志文章,评审
doi:10.1186/s12936-017-1915-8
更新日期:2017-06-29 00:00:00
abstract:BACKGROUND:Plasmodium vivax parasites are the predominant cause of malaria infections in the Brazilian Amazon. Infected individuals are treated with primaquine, which can induce haemolytic anaemia in glucose-6-phosphate dehydrogenase (G6PD)-deficient individuals and may lead to severe and fatal complications. This X-li...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1889-6
更新日期:2017-06-15 00:00:00
abstract::In the past decade, research on the functions of extracellular vesicles in malaria has expanded dramatically. Investigations into the various vesicle types, from both host and parasite origin, has revealed important roles for extracellular vesicles in disease pathogenesis and susceptibility, as well as cell-cell commu...
journal_title:Malaria journal
pub_type: 杂志文章,评审
doi:10.1186/s12936-017-1891-z
更新日期:2017-06-09 00:00:00
abstract:BACKGROUND:Relatively little is known about the prevalence of blood parasites in shorebirds, especially those breeding in the tropics. The prevalence of blood parasites of the genera Plasmodium, Haemoproteus and Leucocytozoon was assessed in blood samples from Kentish plovers and cream-coloured coursers in Cape Verde, ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1892-y
更新日期:2017-06-08 00:00:00
abstract::Most human Plasmodium infections in western Kenya are asymptomatic and are believed to contribute importantly to malaria transmission. Elimination of asymptomatic infections requires active treatment approaches, such as mass testing and treatment (MTaT) or mass drug administration (MDA), as infected persons do not see...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1883-z
更新日期:2017-06-07 00:00:00
abstract:BACKGROUND:Currently available diagnostic techniques of Plasmodium falciparum infection are not optimal for non-invasive, population-based screening for malaria. It was hypothesized that a mass spectrometry-based metabolomics approach could identify urinary biomarkers of falciparum malaria. METHODS:The study used a ca...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1875-z
更新日期:2017-05-30 00:00:00
abstract:BACKGROUND:Malaria during pregnancy is associated with poor maternal and pregnancy outcome and the World Health Organization recommends the administration of intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) and distribution of insecticide-treated mosquito nets (ITNs) to all preg...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1872-2
更新日期:2017-05-25 00:00:00
abstract:BACKGROUND:Malaria transmission in arid and semi-arid regions of Kenya such as Baringo County, is seasonal and often influenced by climatic factors. Unravelling the relationship between climate variables and malaria transmission dynamics is therefore instrumental in developing effective malaria control strategies. The ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1848-2
更新日期:2017-05-25 00:00:00
abstract:BACKGROUND:The United Nation's sustainable development goal for 2030 is to eradicate the global malaria epidemic, primarily as the disease continues to be one of the major concerns for public health in sub-Saharan Africa. In 2015, the region accounted for 90% of malaria deaths. Mozambique recorded a malaria mortality r...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1866-0
更新日期:2017-05-22 00:00:00
abstract:BACKGROUND:Malaria is a widespread infectious disease that threatens a large proportion of the population in tropical and subtropical areas. Given the emerging resistance against the current standard anti-malaria chemotherapeutics, the development of alternative drugs is urgently needed. New anti-malarials representing...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1839-3
更新日期:2017-05-15 00:00:00
abstract:BACKGROUND:Plasmodium falciparum-infected erythrocytes sequester in the microcirculation due to interaction between surface-expressed parasite proteins and endothelial receptors. Endothelial cells are covered in a carbohydrate-rich glycocalyx that shields against undesired leukocyte adhesion. It was investigated if the...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1844-6
更新日期:2017-05-10 00:00:00
abstract:BACKGROUND:Public health facilities are usually the first to receive interventions compared to private facilities, yet majority of health seeking care is first done with the latter. This study compared the capacity to manage acute febrile illnesses in children below 5 years in private vs public health facilities in ord...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1842-8
更新日期:2017-05-02 00:00:00
abstract:BACKGROUND:Transmission of malaria from man to mosquito depends on the presence of gametocytes, the sexual stage of Plasmodium parasites in the infected host. Naturally acquired antibodies against gametocytes exist and may play a role in controlling transmission by limiting the gametocyte development in the circulation...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1827-7
更新日期:2017-04-26 00:00:00
abstract:BACKGROUND:The effectiveness of malaria control programmes through implementation of vector control activities is challenged by the emergence of insecticide resistance. In the South-Eastern region of Côte d'Ivoire, where palm oil plantations remain the predominant agricultural crop, the susceptibility of wild Anopheles...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1804-1
更新日期:2017-04-20 00:00:00
abstract:BACKGROUND:Imported cases of multidrug resistant Plasmodium falciparum and treatment failure with artemisinin-based regimens, although rare, have been described also in Western countries and their management is often challenging. This is also due to an inadequate knowledge and implementation of health prevention measur...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1795-y
更新日期:2017-04-14 00:00:00
abstract:BACKGROUND:In individuals living in malaria-endemic regions, parasitaemia thresholds for the onset of clinical symptoms vary with transmission intensity. The mechanisms that mediate this relationship are however, unclear. Since inflammatory responses to parasite infection contribute to the clinical manifestation of mal...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1796-x
更新日期:2017-04-11 00:00:00
abstract:BACKGROUND:The 2016 World Health Organization (WHO) World Malaria Report documents substantial progress towards control and elimination of malaria. However, major challenges remain. In some regions of Southeast Asia, the simian parasite Plasmodium knowlesi has emerged as an important cause of human malaria, and the aut...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1787-y
更新日期:2017-03-31 00:00:00